AI Stratifies COPD Patients for Gene Therapy Trials: Machine Learning Identifies Responders and Revolutionizes Precision Medicine for Respiratory Disease
Chronic obstructive pulmonary disease (COPD) ranks among the world’s leading causes of morbidity and mortality, affecting over 400 million people globally. Yet COPD is deceptively heterogeneous—a collection of distinct disease mechanisms rather than a single condition. This fundamental heterogeneity has historically confounded therapeutic development, as clinical trials treat COPD as a monolith when underlying disease…